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Why GuideMia

Clear aligner planning · what the sources establish

How orthodontic planning systems actually differ

Eight systems, one criterion per card, every value carrying the source it came from. Seven of them were assessed by a 2025 scoping review that ran each program itself, so some of the absences here were genuinely tested for rather than merely unfound.

Two things to read carefully

“Not offered” and a missing system are different claims. The review obtained every program it assessed and ran each against one fixed list of workflow steps, so a cell saying a step is not offered reports a test. A system absent from a card means no source was found for it, which is a question to put to that vendor.

The review is a dated baseline, not the current product state. Its survey closed in March 2024, and several of these systems have shipped a great deal since — in one case enough to overturn its result outright. Cards carry the review finding followed by the current first-party documentation where it answers the same question.

259statements a source positively documents
9absences somebody actually tested for
316not established — questions, not findings

Show only the systems you are comparing

Where a real comparison exists 28

Three or more systems documented. These are the criteria on which the published material can actually tell systems apart.

3D data the software itself accepts

8 of 8 systems documented

GuideMia OrthoPlus
CBCT as DICOM, optical scans as STL, PLY or OBJ, model scans and facial scans, fused into one model carrying crowns, roots, bone, soft tissue and occlusionGM
BlueSkyPlan
CBCT + IOSR25
Clear Aligner Studio
IOS onlyR25
Maestro 3D Ortho Studio
review: IOS plus CBCT only as an exported STL; current vendor documentation adds CBCT-acquired roots, jaw data and 3D facial scansVEN
Nemocast
IOS + CBCT + facial scanR25
OnyxCeph³
IOS onlyR25
Vision (SoftSmile)
IOS + CBCTR25
ArchForm
IOS onlyR25
This is the row that decides what every automation claim below is worth, and the review draws the line itself with a footnote: Maestro 3D and Orth’up take CBCT in STL format — a mesh somebody already made from the volume, not the volume. Five of the programs the review tested could import a CBCT scan at all. Automation that begins after an export is automation of a later problem.

Automated tooth segmentation from CBCTtested

8 of 8 systems documented

GuideMia OrthoPlus
a local two-stage pipeline, results cached to disk so reopening a case skips work already doneGM
BlueSkyPlan
automated — alone among the programs the review tested, a group that did not include GuideMiaR25
Clear Aligner Studio
not offered — the program takes no CBCT
Maestro 3D Ortho Studio
current software automatically combines scanned crowns with CBCT-acquired roots; full tooth segmentation directly from the volume is not statedVEN
Nemocast
current NemoStudio adds licensed automatic DICOM/model segmentation for teeth, crowns, jaws and related anatomyVEN
OnyxCeph³
not offered — the program takes no CBCT
Vision (SoftSmile)
semi-automaticR25
ArchForm
not offered — the program takes no CBCT
Two populations meet in this row and they are not the same. The review obtained and ran a set of programs of its own choosing; this table shows eight columns, seven of them from that set plus us. GuideMia was never reviewed, so “alone among the programs the review tested” says nothing about our cell either way — it reports what the review found, and our cell reports what we document.

Automated tooth segmentation from the intraoral scan

8 of 8 systems documented

GuideMia OrthoPlus
a separate optical-scan engine running as a local program, upper and lower arches processed in parallelGM
BlueSkyPlan
automatedR25
Clear Aligner Studio
automatedR25
Maestro 3D Ortho Studio
current vendor documents zero-click AI tooth segmentationVEN
Nemocast
current licensed automatic segmentation accepts models as well as DICOMVEN
OnyxCeph³
semi-automaticR25
Vision (SoftSmile)
current vendor documents precise automated anatomical segmentation; the 2024 review recorded it as semi-automaticSS
ArchForm
current vendor workflow states auto segmentation before treatment designAF
Three of the programs automated this when the review surveyed vendors through March 2024. Current vendor documentation now establishes automatic segmentation for additional products, which is why the historical review cells and later vendor updates are labelled separately.

Automated CBCT–intraoral registration and fusiontested

8 of 8 systems documented

GuideMia OrthoPlus
an Automatic Alignment function, with a separate bite-registration path for severe malocclusionGM
BlueSkyPlan
automated — “aligns the surface scan perfectly to the radiographic data”BSB
Clear Aligner Studio
not offered — no CBCT to register
Maestro 3D Ortho Studio
current vendor documents automatic combination of scanned crowns and CBCT-acquired rootsVEN
Nemocast
current NemoStudio documentation describes automatic alignment and segmentation of DICOM and modelsVEN
OnyxCeph³
not offered — no CBCT to register
Vision (SoftSmile)
automatedR25
ArchForm
not offered — no CBCT to register

Facial scan accepted as a planning input

8 of 8 systems documented

GuideMia OrthoPlus
facial scans fuse into the same anatomical modelGM
BlueSkyPlan
not listed among its inputs
Clear Aligner Studio
not listed among its inputs
Maestro 3D Ortho Studio
current vendor documents 3D face scans and patient photographs alongside CBCT jaw dataVEN
Nemocast
listed among its 3D inputsR25
OnyxCeph³
not listed among its inputs
Vision (SoftSmile)
not listed among its inputs
ArchForm
not listed among its inputs

What the automation covers — planning, design, or production output

7 of 8 systems documented

GuideMia OrthoPlus
one run crosses all three: setup, IPR, occlusion and staging (planning); aligner and arch models, attachments as geometry, bonding guides and trim paths (design); then case tags, laser-marking offsets and a trimmer fixture definition (production output)GM
BlueSkyPlan
planning automated throughout, plus printable aligner design and an automated trim-line script; no production-machine integration documentedBSB
Clear Aligner Studio
planning and aligner design within the wider 3Shape workflowVEN
Maestro 3D Ortho Studio
the same span is documented — segmentation and setup, then transition models, direct-print aligners and 3D labels, then CNC and laser trimming integrationVEN
OnyxCeph³
planning and appliance design across modules, with production tied to the LAB editionONX
Vision (SoftSmile)
planning and staging, plus print and model adjustment with blockouts; production handoff not documentedSS
ArchForm
planning, with export automatically optimised for printingAF

Not established from public documentation for Nemocast.

The review’s nine steps are all planning steps. Segmentation, registration, arch curve, movement, occlusion, IPR, attachments, staging — the job ends there, and design begins. Models, trim paths, bonding guides and marking are the half a lab actually spends its hours on, and no column in the published comparison reaches them. Anyone comparing “automation” across these systems from that paper alone is comparing the first third of the work.

Steps automated, of the nine assessed

8 of 8 systems documented

GuideMia OrthoPlus
not assessed — GuideMia was not among the programs the review tested. The nine are the review’s list, and our automatic run covers work it has no column for: see the rows belowGM
BlueSkyPlan
9 of 9 — “the sole program with all steps fully automated” among the programs the review testedR25
Clear Aligner Studio
5 of 9R25
Maestro 3D Ortho Studio
1 of 9R25
Nemocast
2 of 9R25
OnyxCeph³
0 of 9 — semi-automatic or manual throughoutR25
Vision (SoftSmile)
3 of 9R25
ArchForm
2 of 9R25
The review is a useful dated baseline, not a live leaderboard. Its vendor survey closed in March 2024; current first-party documentation below records later capabilities without rewriting the review’s original nine-step scores. The review could not confirm whether BlueSkyPlan’s nine were AI-driven, and none of the surveyed programs had been clinically evaluated in the forty-one included studies — so these scores report what runs, never what works clinically.

Occlusal analysistested

8 of 8 systems documented

GuideMia OrthoPlus
automatic occlusion adjustment and automatic dental occlusal changes, with an occlusion distance map to read the resultGM
BlueSkyPlan
automatedR25
Clear Aligner Studio
not offered
Maestro 3D Ortho Studio
semi-automaticR25
Nemocast
automatedR25
OnyxCeph³
semi-automaticR25
Vision (SoftSmile)
not offered
ArchForm
not offered
Four of the programs the review tested offer no occlusal analysis step at all, including two that automate the most elsewhere. A tested absence, not a gap in the research.

Interproximal reduction and collision planning

8 of 8 systems documented

GuideMia OrthoPlus
automatic IPR honouring per-tooth allowed limits, with a live collision check against neighboursGM
BlueSkyPlan
automatedR25
Clear Aligner Studio
automatedR25
Maestro 3D Ortho Studio
semi-automaticR25
Nemocast
automatedR25
OnyxCeph³
semi-automatic; movement increments calculated against “user-specified limits for all components of tooth movement, including IPR”ONX
Vision (SoftSmile)
automated; the vendor describes simulating and planning IPR “to make space between teeth”SS
ArchForm
manual in the review; the vendor markets fine-tuning of staging, attachments and IPRAF

Attachment positioning

8 of 8 systems documented

GuideMia OrthoPlus
automatic attachments, with force ridges, button platforms and cutouts placed alongside themGM
BlueSkyPlan
“populated instantly utilizing automated placement logic”, with manual overrideBSB
Clear Aligner Studio
automatedR25
Maestro 3D Ortho Studio
manualR25
Nemocast
manualR25
OnyxCeph³
attachments “applied to support individual movements”, with an attachment designer and multiple attachments per crownONX
Vision (SoftSmile)
pre-loaded attachment libraries, automatic placement rules, customisable shapes and sizesSS
ArchForm
semi-automaticR25

Automatic alignment steered by named clinical parameters

4 of 8 systems documented

GuideMia OrthoPlus
a treatment-plan dialog of real quantities rather than a strength slider: expansion −15 to 15 mm in 0.25 steps (“negative value means retraction”), anterior extrusion/intrusion −6 to 6, curve of Spee height and molar vertical deviation on the lower arch, sagittal and coronal inclination levels −20 to 20, and distalization −15 to 15 — with a <strong>crowdedness figure recomputed as they change</strong>, because “the combination of expansion, protraction and distalization determines the final crowdedness”. The dialog calls its own values “rough estimations”GM
OnyxCeph³
movement increments calculated against “user-specified limits for all components of tooth movement, including IPR”ONX
Vision (SoftSmile)
an automated planner the vendor describes as working from real-time stress calculation and biomechanics, rather than from prescribed arch quantitiesSS
ArchForm
the vendor markets fine-tuning of staging, attachments and IPR; a clinical-parameter dialog of this kind is not documentedAF

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast.

Two different ideas of control sit in this row and the table should not flatten them. One sets limits the engine must respect — how much IPR, how much movement per step. The other sets clinical intent the engine plans toward — this much expansion, this much distalization, this curve of Spee — and reports back whether the arch can take it. Ours is the second kind, and the crowdedness readout is what makes it a conversation rather than a setting.

Attachment library, and whether you can bring your own

4 of 8 systems documented

GuideMia OrthoPlus
twenty-six built-in types from root-control pairs to anchorage and rotation shapes, ending in a user-defined entry: “when you select the user-defined, you can choose an STL file from your system and add it as attachment”, with advice to put the origin about a third of the thickness up from the base. The entry is tier-gated — the chairside edition does not offer itGM
Maestro 3D Ortho Studio
customisable attachment library and creation of custom geometries; outside-file import is not statedVEN
OnyxCeph³
an attachment designer, and multiple attachments per crown; importing an outside file is not documentedONX
Vision (SoftSmile)
pre-loaded attachment libraries with customisable shapes and sizes; importing an outside file is not documentedSS

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Nemocast, ArchForm.

“Customisable attachments” does not mean one thing. Adjusting a vendor shape, drawing a new geometry in the vendor’s designer, and loading an outside STL are three different degrees of freedom; the table keeps them separate rather than converting all three into the same yes.

Treatment staging

8 of 8 systems documented

GuideMia OrthoPlus
automatic staging with step-count balancing and simulationGM
BlueSkyPlan
automatedR25
Clear Aligner Studio
automatedR25
Maestro 3D Ortho Studio
semi-automaticR25
Nemocast
semi-automaticR25
OnyxCeph³
movement increments calculated between initial and target situation, with intermediate steps added on a timelineONX
Vision (SoftSmile)
semi-automatic in the review; the vendor markets “comprehensive and intuitive staging” with group movementSS
ArchForm
automatedR25

Attachments and brackets removed from a scanned model

4 of 8 systems documented

GuideMia OrthoPlus
a Remove Attachment tool appears in two toolbars — the model-fixing set beside sculpt and define-area, and the crown-boundary set. Its status tip is not recorded in our support library, so what it removes is stated here no further than thatGM
Maestro 3D Ortho Studio
current toolset includes bracket-removal tools for scan cleanupVEN
OnyxCeph³
Bracket Erase 3D is a named moduleONX
Vision (SoftSmile)
manual removal of retainers, attachments and scan artifacts is documentedSS

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Nemocast, ArchForm.

The row where our own documentation is the weakest link. Three rivals describe this plainly — Maestro 3D ships bracket-removal and scan-cleanup tools, OnyxCeph has a module called Bracket Erase 3D, SoftSmile documents manual removal of retainers and attachments — while our Remove Attachment tool sits in two toolbars with no recorded status tip. Its company there suggests cleaning bonded hardware off a scan, which would matter on exactly the re-scan cases the restart workflow exists for, but suggests is not documents and the cell stays partial until somebody writes the tip down.

Marking data generated onto the arch models

5 of 8 systems documented

GuideMia OrthoPlus
generated inside the automatic run rather than placed by hand — a case tag carrying the step number and case identifier, embossed on or cut into every model, placed then repositioned and resized; it can be tagged on the arch as a protrusion or on the crown, and direct-print runs additionally carry laser-marking offsets written for FDI 16/26 and 36/46GM
BlueSkyPlan
labels can be propagated across all intermediate modelsBSB
Maestro 3D Ortho Studio
automatic model labels are documentedVEN
OnyxCeph³
serial export labels accept patient and treatment-step placeholdersONX
ArchForm
print output is automatically labelledAF

Not established from public documentation for Clear Aligner Studio, Nemocast, Vision (SoftSmile).

Production rather than planning, and the row filled up once current vendor documentation was read: five of the eight label their output, by propagated labels, placeholders in a serial export, or automatic print labelling. No planning-software review scores any of it, which is why the review’s grid shows nothing here and this row had to be built from first-party material.

Treatment report with movements, IPR and attachments

5 of 8 systems documented

GuideMia OrthoPlus
movement tables and plan data are available inside the caseGM
BlueSkyPlan
Tooth Movement Report provides original-to-final and step-to-step angles and displacementsBSB
Maestro 3D Ortho Studio
PDF report includes treatment movements and treatment-design dataVEN
Nemocast
NemoCeph and NemoCast generate configurable treatment reportsVEN
OnyxCeph³
movement tables plus IPR and attachment information are available in the treatment workflowONX

Not established from public documentation for Clear Aligner Studio, Vision (SoftSmile), ArchForm.

Open production export formats

6 of 8 systems documented

GuideMia OrthoPlus
step or range export as PLY, with STL/PLY/OBJ accepted elsewhere in the workflowGM
BlueSkyPlan
STL production export; segmented structures can also be exportedBSB
Maestro 3D Ortho Studio
STL, PLY and OBJ are documented open formatsVEN
OnyxCeph³
STL, OBJ, PLY, OFF and DXF export are documentedONX
Vision (SoftSmile)
STL and OBJ export are documentedSS
ArchForm
optimized STL output for printingAF

Not established from public documentation for Clear Aligner Studio, Nemocast.

Browser-based viewer for a finished plan

4 of 8 systems documented

GuideMia OrthoPlus
a web review path, with cloud save and open, and cases sendable to GuideMia for reviewGM
Maestro 3D Ortho Studio
Maestro Cloud includes a web viewer for shared casesVEN
OnyxCeph³
a webview link can be exported for browser reviewONX
Vision (SoftSmile)
Vision Viewer gives “secure, browser-based access to treatment plans from any device”SS

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Nemocast, ArchForm.

Doctor–lab collaboration, comments and approval

5 of 8 systems documented

GuideMia OrthoPlus
cloud save/open and a web review route support case sharingGM
Clear Aligner Studio
3Shape describes integrated in-house and doctor–lab clear-aligner workflowsVEN
Maestro 3D Ortho Studio
cloud collaboration includes messaging, review and approvalVEN
OnyxCeph³
Lab Portal supports shared web review, feedback and approvalONX
Vision (SoftSmile)
browser Viewer/Editor supports review, comments, editing and approvalSS

Not established from public documentation for BlueSkyPlan, Nemocast, ArchForm.

Progress monitored against the plan from a later scan

4 of 8 systems documented

GuideMia OrthoPlus
deviations from the plan shown as a colour map, with progress monitoring handled through Cympha StudioGM
BlueSkyPlan
BlueSkyMonitoring is the vendor's remote monitoring workflowBSB
Maestro 3D Ortho Studio
Check and Correct compares a control scan with the planned transition modelsVEN
Vision (SoftSmile)
“upload any progress scan. Instantly see deviations from plan — down to the exact tooth”SS

Not established from public documentation for Clear Aligner Studio, Nemocast, OnyxCeph³, ArchForm.

Mid-treatment restart from an intermediate scan

5 of 8 systems documented

GuideMia OrthoPlus
a designed workflow rather than a workaround: load a jaw intermediate scan, set the restart point, replan from that step and simulate the new plan beside the old one, with revisions savedGM
BlueSkyPlan
“midcourse adjustments are now faster with automatic replanning based on initial treatment goals”BSB
Maestro 3D Ortho Studio
Check and Correct updates treatment from a control scan while preserving the planned endpointVEN
Vision (SoftSmile)
re-plan mid-course from an uploaded progress scanSS
ArchForm
refinements turned around in a dayAF

Not established from public documentation for Clear Aligner Studio, Nemocast, OnyxCeph³.

Five of the eight document some form of mid-course replanning. What differs is mechanism: refinement turnaround, deviation review, automatic replan, or a restart anchored to a matched treatment step.

Appliances beyond aligners and brackets

4 of 8 systems documented

GuideMia OrthoPlus
expanders, twin blocks, bite ramps anterior and posterior, force ridges, button platforms and cutouts, mandibular advancement wings, and mini-TAD planning with a doubled base-model marginGM
Maestro 3D Ortho Studio
retainers, bite splints, expanders and mandibular-advancement / twin-block appliancesVEN
Nemocast
mandibular repositioning, micro-screw and corticotomy guides, plus integrated orthodontic appliance workflowsVEN
OnyxCeph³
Retainer, Bite Splint, TADmatch and other named 3D modulesONX

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Vision (SoftSmile), ArchForm.

Direct-print aligner design

6 of 8 systems documented

GuideMia OrthoPlus
aligner models for direct printing generated automatically, with printer clearance and thickness as parametersGM
BlueSkyPlan
“Design Printable Aligners”BSB
Maestro 3D Ortho Studio
direct-print aligners with variable thickness are documentedVEN
Nemocast
direct-print aligner production is documentedVEN
OnyxCeph³
positive/direct aligner export is documented as pre-release and requires Bite Splint 3DONX
Vision (SoftSmile)
print and model adjustment with hollow, ribbed, solid and custom blockouts — model preparation for printing rather than a printed alignerSS

Not established from public documentation for Clear Aligner Studio, ArchForm.

Automatic trim path for a robotic trimmer

5 of 8 systems documented

GuideMia OrthoPlus
a trimming path generated from the aligner boundary and a named fixture definition — GuideMia fixture, Ortho-automation fixture or a custom jig file — emitting a coordinate file and a review STL per stepGM
BlueSkyPlan
“Design Aligner Trim Curve: creates an automated trim line script” — a trim line, with no fixture definition documentedBSB
Maestro 3D Ortho Studio
automatic CNC/laser trim integration is documentedVEN
Nemocast
CNC cutting integration is documented for aligner productionVEN
OnyxCeph³
trimline propagation and configurable export are documented; a fixture-specific robotic path is notONX

Not established from public documentation for Clear Aligner Studio, Vision (SoftSmile), ArchForm.

The distinction in this row is the fixture. A trim curve is a line on a model; a trim path is that line expressed for a particular robotic trimmer’s jig. Blue Sky Bio documents the first. Trimming belongs to production rather than planning, which is exactly the kind of capability a planning-software review would not think to score.

Planning available as a service, with no local install

4 of 8 systems documented

GuideMia OrthoPlus
cases can be sent to ClearAligner.AI, which returns an AI-made design, and to the GuideMia design service — a route for a practice that wants the output without running the software or the workstationGM
BlueSkyPlan
optional services alongside the softwareBSB
Vision (SoftSmile)
planning services alongside the platformSS
ArchForm
a concierge planning option alongside self-planningAF

Not established from public documentation for Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³.

A different answer to the same question as the chairside edition below: who does the work. A lighter edition keeps it in the building; a service sends it out and brings back a design. Most of this field offers the second, which is worth knowing before reading any claim about how little time a plan takes.

Desktop or cloud

8 of 8 systems documented

GuideMia OrthoPlus
desktop on the operator’s own workstation, with an optional cloud design system that can run in the customer’s own account or on-premiseGM
BlueSkyPlan
computer-basedR25
Clear Aligner Studio
computer-basedR25
Maestro 3D Ortho Studio
Windows desktop plus Maestro Cloud collaborationVEN
Nemocast
computer-basedR25
OnyxCeph³
computer-basedR25
Vision (SoftSmile)
cloud browser Viewer/Editor plus production workflowSS
ArchForm
desktop planning with cloud-connected servicesAF

Access

8 of 8 systems documented

GuideMia OrthoPlus
licensed, with published pricingGM
BlueSkyPlan
free desktop download; production STL exports are purchasedBSB
Clear Aligner Studio
closedR25
Maestro 3D Ortho Studio
closedR25
Nemocast
closedR25
OnyxCeph³
closedR25
Vision (SoftSmile)
closedR25
ArchForm
closedR25

Documented licensing shape — different models, not different prices

4 of 8 systems documented

GuideMia OrthoPlus
subscription to the desktop editions, plus optional cloud design servicesGM
BlueSkyPlan
free planning software with paid production exports and optional servicesBSB
Maestro 3D Ortho Studio
Expert licensing or pay-per-use accessVEN
OnyxCeph³
modular PRO / LAB editions; open 3D export is tied to LABONX

Not established from public documentation for Clear Aligner Studio, Nemocast, Vision (SoftSmile), ArchForm.

Partially documented 14

One or two systems documented. Enough to know the criterion matters, not enough to compare across the field.

Virtual roots created where the case has no CBCT

2 of 8 systems documented

GuideMia OrthoPlus
Create Virtual Roots builds them for segmented teeth, so movement is planned against the whole tooth rather than the crown; anatomical roots are used instead when a volume is presentGM
Maestro 3D Ortho Studio
current technical specifications include virtual roots as well as CBCT-acquired rootsVEN

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

2D / 3D cephalometric analysis and growth prediction

3 of 8 systems documented

GuideMia OrthoPlus
offered through Cympha Studio rather than inside OrthoPlus — a separate product in the same stable, which is a different answer from having it in the plannerGM
Nemocast
NemoCeph documents 2D and 3D cephalometry, facial analysis, growth prediction and report generationVEN
OnyxCeph³
the official module index lists Ricketts V.T.O. among the 2D modules; no 3D cephalometric module appears on that index, so 3D is not confirmed hereONX

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Vision (SoftSmile), ArchForm.

Automatic undercut filling on arch models

2 of 8 systems documented

GuideMia OrthoPlus
undercuts filled and evaluated against the chosen insertion direction, with the option to reuse the previous step’s fillings so consecutive models stay consistentGM
Vision (SoftSmile)
print and model adjustment offers “hollow, ribbed, solid, and custom blockouts”SS

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, ArchForm.

Tooth extraction handled as a planning case, not a deletion

3 of 8 systems documented

GuideMia OrthoPlus
a 32-tooth extraction chart, automatic extraction within the run, extraction applied to the original tissue at step 0, plus spacers as virtual teeth, space kept for missing teeth and an emerging-cap option for a replacing toothGM
Maestro 3D Ortho Studio
virtual extraction with gingival reconstructionVEN
Nemocast
virtual extraction with gingival deformation in the aligner workflowVEN

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, OnyxCeph³, Vision (SoftSmile), ArchForm.

All-in-one model fixing, with the manual toolbox beside it

3 of 8 systems documented

GuideMia OrthoPlus
one All-in-One Fix across the jaw, sitting in a toolbox with fix-quality-issues, fill holes, reduce triangles, trim model, smooth, sculpt and define-area; the product’s own advice is to do the targeted fixes first — “if you want to fix plaster model bubbles, extend models, trim model boundary” — rather than reach for the one buttonGM
Maestro 3D Ortho Studio
AI scan correction and automatic model preparation are documented in the current workflowVEN
OnyxCeph³
3D export includes automatic inspection and repair plus hollowing, offset and perforation controlsONX

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Nemocast, Vision (SoftSmile), ArchForm.

Staging by key frame rather than by hand-built phases

3 of 8 systems documented

GuideMia OrthoPlus
automatic staging sets a key frame per tooth — “a tooth position where the tooth will have to be during the movement process”, marked red in the movement table — and adds steps where a collision demands itGM
OnyxCeph³
increments calculated between initial and target situation, with intermediate steps added on a timelineONX
Vision (SoftSmile)
group movement within stagingSS

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, ArchForm.

A tooth moved mid-course, and the staging re-derived around it

3 of 8 systems documented

GuideMia OrthoPlus
round-tripping rather than nudging: the move-at-step toggle is available <strong>only when the selected cell is a key frame</strong>, so the edited position becomes a constraint the plan must pass through, not a change the next recompute discards. Automatic staging then reruns the movements “in the middle of the simulation so that all the collisions will be eliminated”, adding steps where the new constraint needs themGM
OnyxCeph³
intermediate steps can be added on the timeline and checked or adjusted; whether editing one re-derives the rest is not documentedONX
Vision (SoftSmile)
staging adjustments can be requested and the staging engine recalculates for the next revision — a revision cycle rather than an edit that resolves in placeSS

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, ArchForm.

The question behind this row is what happens to your edit. A mid-course position is only useful if the automation is obliged to honour it; otherwise the next recompute quietly undoes the clinician’s judgement and the plan looks automatic right up until it is wrong. Nothing in the review measures this, because its staging column scores whether staging runs automatically, not whether it survives being corrected.

Collisions removed automatically across every step, not just at setup

3 of 8 systems documented

GuideMia OrthoPlus
movements re-run mid-simulation so collisions are eliminated across the whole plan, with an aggressive mode and a recalculate-collisions-and-gaps pass over the finished stagingGM
Maestro 3D Ortho Studio
its own staging material describes the software “automatically detecting collisions and spaces” to guide how movements are distributed across macro and micro stagingVEN
Vision (SoftSmile)
“detects and visualizes potential collisions between teeth during treatment” and “automatically adjusts the treatment plan to resolve collisions”SS

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Nemocast, OnyxCeph³, ArchForm.

The review scores collision once, inside IPR planning, so its grid cannot show collision work done before planning begins or again across a finished plan. Current SoftSmile and Maestro documentation adds evidence beyond that older instrument; remaining blanks are questions, not findings.

Tooth movement recorded as a video from inside the application

3 of 8 systems documented

GuideMia OrthoPlus
“everything happens within this image window will be captured. Click the button again to save as an mp4 file” — so a movement playback, with soft tissue if wanted, becomes a file to send without screen-recording softwareGM
BlueSkyPlan
the current manual documents video exportBSB
Maestro 3D Ortho Studio
video report is part of the sharing workflowVEN

Not established from public documentation for Clear Aligner Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

The step the patient actually reached, found by the software

3 of 8 systems documented

GuideMia OrthoPlus
the step number the operator enters is a hint rather than the answer: “the system will try to match the new scan with original plan and find the most fit step of the treatment. For example, the current step should be 10, but the scan may match with step 8, which means the restart should start from step 8”. The replan then runs from the matched step, and the control text tells the clinician how to make the match reliable — “remove the existing attachments on the patient’s teeth so that the system can better identify the actual treatment status”GM
Maestro 3D Ortho Studio
Check and Correct automatically identifies the transition model that best matches the current scanVEN
Vision (SoftSmile)
a progress scan is matched against the plan and deviation reported tooth by tooth; working out which planned step the dentition has reached is not something the documentation claims the software doesSS

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Nemocast, OnyxCeph³, ArchForm.

The capability is now documented in two products here: GuideMia and Maestro 3D. Patent literature also describes matching a current scan against planned stages, so it should not be presented as a newly invented idea. The useful comparison is operational: whether the match only reports deviation or also establishes the restart point for a revised plan.

Several treatment plans kept side by side and switched between

3 of 8 systems documented

GuideMia OrthoPlus
revisions saved as whole plans — “one plan is defined as the tooth positions and attachments or brackets” — listed in the case information table and made current on demandGM
Maestro 3D Ortho Studio
multiple virtual setup projects can be retained for a caseVEN
Nemocast
treatment timelines can be overlaid for comparison; switching complete alternative plans is not statedVEN

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, OnyxCeph³, Vision (SoftSmile), ArchForm.

Two different operations wear the same name. With a new scan, the question is where the patient actually is, and the replan drives from there toward the endpoint. Without one, a planned step becomes the baseline and what follows is revised. Current documentation now distinguishes several mechanisms, but only GuideMia explicitly documents both operations and the rule that already-manufactured steps remain untouched.

Planned alongside anchorage implants, with the implant view to match

3 of 8 systems documented

GuideMia OrthoPlus
anchorage implants added to the ortho case, made parallel to one another, and read on an implant-centric cross-section view — the surgical-guide engine working inside the orthodontic planGM
Nemocast
micro-screw and corticotomy guides are documented in the orthodontic workflowVEN
OnyxCeph³
used for virtual planning of TAD positions and the design of insertion guidesLIT

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Vision (SoftSmile), ArchForm.

Orthodontic and implant planning share case data or a platform environment

3 of 8 systems documented

GuideMia OrthoPlus
OrthoPlus and Implant Master operate in the same GuideMia/Cympha case environment and share local case dataGM
BlueSkyPlan
implant and orthodontic modules are inside the same BlueSkyPlan applicationBSB
Nemocast
NemoCast and NemoScan are integrated modules within NemoStudio's multidisciplinary environmentVEN

Not established from public documentation for Clear Aligner Studio, Maestro 3D Ortho Studio, OnyxCeph³, Vision (SoftSmile), ArchForm.

Acid-etching guide

2 of 8 systems documented

GuideMia OrthoPlus
generated alongside the bonding guideGM
Maestro 3D Ortho Studio
an acid-etching guide is documented in the current orthodontic workflowVEN

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Where only GuideMia’s documentation answers 27

Capabilities GuideMia publishes in detail, and for which no public source was found elsewhere. Read the silence carefully — it is a question about the other systems, not an answer about them.

Occlusal plane detected automatically from the jaw model

1 of 8 systems documented

GuideMia OrthoPlus
the AI engine creates the datum plane the whole case is then referenced to, with nothing for the operator to decide; the manual fallback is four points — “two points on the molar or premolar, at the centers of those teeth, and two points on the incisors at middle lines of the lingual surfaces” — and our own automation map calls this the first hard AI dependency in the cascadeGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Not one of the review’s nine, and foundational to all of them: tooth orientation, arch curves, staging and model generation are all expressed against this plane. Worth reading as a dependency as much as a capability — without the engine it is four clicks, and every later automatic step inherits whatever the plane got wrong.

The whole automatic run works on a CBCT case, not only an intraoral one

1 of 8 systems documented

GuideMia OrthoPlus
the cascade covers the CBCT path end to end — bone isolated from the volume, scan registered to it, teeth segmented by the CBCT engine, roots created, apical centres taken from the CT slices — and then continues into setup, staging and model generation without changing routeGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

The hardest version of the automation question, and the one no published source answers for anybody. Automating a setup from an intraoral scan is a surface problem. Automating it from a volume means isolating bone, registering two modalities, segmenting against scatter and carrying roots through every later step. BlueSkyPlan automates each of those steps individually — the review scored it so — but whether the whole CBCT path runs as one unbroken automatic sequence is not something its documentation or the review states either way.

Apical centres taken from the CT slices

1 of 8 systems documented

GuideMia OrthoPlus
on a CBCT case the run reads apical centres from the slices; outside an automatic run the operator double-clicks to define them in the 2D viewsGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Root apex movement reported as a number

1 of 8 systems documented

GuideMia OrthoPlus
the movement table reports root-centre translation beside crown-centre translation and top translation, so apex travel is read off rather than inferred from a pictureGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Bone density shown on the root surface while movement is simulated

1 of 8 systems documented

GuideMia OrthoPlus
a bone density map requiring both a loaded CBCT and a virtual root on the tooth — switching it on turns the roots on with it, so density is read where the root actually isGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

The strongest cluster in the table, and the reason is structural rather than clever: most of this field never takes a volume, so there is no bone to render density on and no anatomical root to render it against. Blue Sky Bio argues the same clinical point in its own words — real roots and cortical plates on screen are what stop you “driving roots out of the cortical bone plate” — which makes it the one program here that could answer these rows, and its documentation does not.

Virtual tissue model, editable

1 of 8 systems documented

GuideMia OrthoPlus
a virtual tissue model with local deformation, a soft-tissue amount with reduction and grafting, and a Sync Tissue repair for when tissue stops following the teeth during playbackGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Soft tissue moves with the teeth through the simulation

1 of 8 systems documented

GuideMia OrthoPlus
playback with soft tissues, and tissue morphing carried into the generated modelsGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Automatic gap and collision correction on the segmentation itself

1 of 8 systems documented

GuideMia OrthoPlus
gaps and collisions between segmented teeth calibrated <strong>within 0.2 mm</strong> before planning starts, on the product’s own reasoning that “the tooth segmentation represents the scan data but not the actual teeth”; larger ones are left to the operatorGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Tooth boundary editable after planning is finished

1 of 8 systems documented

GuideMia OrthoPlus
boundaries can be adjusted, tracked, previewed and smoothed per tooth or across the jaw at any point, with crown fixing reversible for the whole jaw in one actionGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Worth separating from segmentation accuracy, which every vendor claims. The question here is whether the boundary is still editable once staging and models exist, or whether correcting it means starting the case again. No rival documentation reviewed answers it either way.

Virtual teeth added where a tooth is missing

1 of 8 systems documented

GuideMia OrthoPlus
“Add virtual teeth to the current jaw. In case of missing teeth, you have two options” — a tooth model is chosen, placed in the 3D view and then sized and oriented by its bounding box; separately, spacers can hold the gap and the treatment plan carries its own missing-teeth pickersGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Crown shape replaced for an erupting tooth

1 of 8 systems documented

GuideMia OrthoPlus
an emerging-cap option where “the added virtual tooth will occupy the place the original tooth is, and inherit its movements” and “must be bigger than the original tooth” — the point being to leave room on the aligner “to facilitate tooth growth and movements”GM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

A mixed-dentition row rather than an adult-aligner one, and the reason it is worth having: a growing patient is the case where a setup made from today’s crowns stops being true during treatment. Nothing in the reviewed field speaks to it either way, and the review’s nine steps have no column where it would appear.

Key frames aligned across several teeth at once

1 of 8 systems documented

GuideMia OrthoPlus
select cells across several teeth with one key frame among them and the tool “will find the closest position of the other selected teeth, set those steps as key frames for those teeth” — turning a position one tooth reaches into a movement stage shared by all of themGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Movement table editable directly, step by step and tooth by tooth

1 of 8 systems documented

GuideMia OrthoPlus
rows are teeth and columns are steps; a tooth can be moved at a given step, steps and stages inserted or deleted, and per-step movement caps set against the planGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Pre-angulation and pre-expansion applied ahead of staging

1 of 8 systems documented

GuideMia OrthoPlus
both sit on the stage-planning dock below the movement matrix — a pre-expansion value in millimetres with an apply, and a pre-angulation slider running between a mesial and a distal side with an apply and a clear — but our own support library records no tooltip for either and flags them as needing confirmation of what they do and their unitsGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Two shipping controls our own documentation cannot describe. They are here because omitting them would be the more dishonest choice, and marked partial rather than yes because a capability we cannot explain is not one we can put in front of a buyer. Documenting them is on the list below.

Overcorrection planned explicitly

1 of 8 systems documented

GuideMia OrthoPlus
an overcorrection control in the movement planGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Arch and aligner models reviewed inside the application before export

1 of 8 systems documented

GuideMia OrthoPlus
a review pass over generated models with a combined model built for the purpose, a full model inspection and its own inspection window, stepping through the setGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

One combined file per planning step

1 of 8 systems documented

GuideMia OrthoPlus
every visible object for a step — teeth, gums, attachments, brackets — exported as a single PLY, for one step or for the whole range at onceGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

An unglamorous row that decides whether a plan can be discussed outside the software. A per-step STL set is a folder somebody has to reassemble; one file per step is a thing you can send. Serial export of the aligner series is documented for OnyxCeph³, but as a series of models rather than a combined object per step.

Replanning from a chosen step with no new scan at all

1 of 8 systems documented

GuideMia OrthoPlus
a restart point set on an existing plan: “for an existing plan, or even treatment course that has been going on, you can set a step as a start point, replan the steps after the given step” — the doctor takes step 20 as the baseline because it is working, not because anything went wrongGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Steps already manufactured left untouched by the revision

1 of 8 systems documented

GuideMia OrthoPlus
“keep existing moving steps from step 0 to given step. New movements will only impact the moving steps after this” — so changing the final positions does not invalidate aligners that already existGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Movements added to a plan that is already finished

1 of 8 systems documented

GuideMia OrthoPlus
a separate mechanism for a separate problem: “an initial plan was done, aligners have been made, and the treatment has finished, but the orthodontist decides to make additional movements … the system will not need to replan the finished steps”GM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

One trigger runs the whole cascade without stopping

1 of 8 systems documented

GuideMia OrthoPlus
the Aligner Bot button presses the step button for the user to the end of the cascade — about forty steps — “you can just enjoy your time and watch this to be finished”GM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Confirmation prompts suppressed for the duration of a run

1 of 8 systems documented

GuideMia OrthoPlus
every confirmation prompt is suppressed while an automatic run is in flight — the AI-engine offer, the use-AI question, the setup dialogGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Headless dispatch from a case-definition file

1 of 8 systems documented

GuideMia OrthoPlus
the application launches with a case-definition file instead of a case opened by hand; that starts an automatic run immediately and the scope dialog is skipped entirelyGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

Scope and aligner step range supplied by that file

1 of 8 systems documented

GuideMia OrthoPlus
the file names which scope to run and the first and last aligner steps to generateGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

These four are not in the review’s instrument, so the blanks are not findings. Ruiz et al. scored whether a step can run automatically, never whether a person has to sit between the steps and answer dialogs. That is the distinction this product turns on — automatic is a property of a step, unattended is a property of a run — and nothing published measures it either way. Establishing it for the other seven means opening each program and trying, which is honest work to do rather than something to assert here.

A chairside edition on the same engine

1 of 8 systems documented

GuideMia OrthoPlus
OrthoClic runs the same engine on an all-automatic chairside route for a practice that wants a plan in minutes without doing the design, with a quick-planning entry point; a case can move between the twoGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

A product-shape question rather than a feature, and it answers a different buyer. The comparable move in this field is a concierge planning service — somebody else designs the case — rather than a lighter edition of the same software on the same engine. Those are not the same thing: one keeps the work in the building, the other sends it out.

Audio walkthrough of the software’s own functions

1 of 8 systems documented

GuideMia OrthoPlus
audio navigation, in-productGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

CBCT segmentation runs on the operator’s own machine

1 of 8 systems documented

GuideMia OrthoPlus
the AI engine installs into a folder under the user’s profile and the only network traffic is fetching that archive; case data stays in files wherever the user puts themGM

Not established from public documentation for BlueSkyPlan, Clear Aligner Studio, Maestro 3D Ortho Studio, Nemocast, OnyxCeph³, Vision (SoftSmile), ArchForm.

What the rivals are genuinely strong at, because a comparison showing everyone else uniformly behind is not believed and should not be. BlueSkyPlan: automation across every planning step the review measured, from a freely downloadable program — though its production exports are bought per case, which is a different shape of cost from a subscription rather than a smaller one, and a lab at volume and a practice doing occasional cases will reach opposite conclusions. Maestro 3D: the broadest documented span in this table, from CBCT-acquired roots through direct-print aligners, progress-scan correction and CNC or laser integration. NemoStudio: orthodontic, cephalometric, surgical and implant modules inside one multidisciplinary platform. OnyxCeph: cephalometric depth and modular appliance design with configurable laboratory production. 3Shape: an established scanner, laboratory and doctor-collaboration ecosystem around the planner. Two strengths often listed for others are left out on purpose — browser review with progress monitoring, and a focused in-office production workflow — because the rows above show us meeting both, and crediting a rival with something you equal misleads in the other direction.

What every system does 4

Criteria met right across the field. Worth seeing so that nothing here gets mistaken for a differentiator.

Model fabrication

8 of 8 systems documented

GuideMia OrthoPlus
Create Base Model, plus an All-in-One Fix and a separate repair toolboxGM
BlueSkyPlan
automatedR25
Clear Aligner Studio
automatedR25
Maestro 3D Ortho Studio
current vendor documents automatic transition-model generation with hollow/grid/drainage options; the review recorded manual fabricationVEN
Nemocast
semi-automatic in the reviewR25
OnyxCeph³
semi-automatic in the review; current tools also inspect, repair, hollow, offset and perforate printable modelsONX
Vision (SoftSmile)
semi-automatic in the review; current print tools generate hollow, ribbed, solid and custom-blockout modelsSS
ArchForm
current workflow automatically prepares optimized, labelled STL print models, including hollow honeycomb output; the review recorded manual fabricationAF

Arch curve building

8 of 8 systems documented

GuideMia OrthoPlus
one arch curve per jaw, derived either from jaw width and length, which is the default, or as a spline through the facial centre points, with editable control points; then automatic arrangement onto that curve, with partial-strength and fine-adjustment variants. The coupling is documented: arch width in the molar area is what “the initial automatic setup will be generated according to”GM
BlueSkyPlan
automatedR25
Clear Aligner Studio
semi-automaticR25
Maestro 3D Ortho Studio
manualR25
Nemocast
manualR25
OnyxCeph³
manualR25
Vision (SoftSmile)
semi-automaticR25
ArchForm
automatedR25

Tooth movement

8 of 8 systems documented

GuideMia OrthoPlus
automatic setup, then every stage remains adjustableGM
BlueSkyPlan
automatedR25
Clear Aligner Studio
manualR25
Maestro 3D Ortho Studio
manualR25
Nemocast
manualR25
OnyxCeph³
semi-automaticR25
Vision (SoftSmile)
automatedR25
ArchForm
manualR25

Bracket placement and indirect bonding guides

6 of 8 systems documented

GuideMia OrthoPlus
bracket placement from the arch curve, bracket bases conformed to the tooth surface continuously, bonding guide generated by wire and trimmed by profileGM
BlueSkyPlan
current manual documents bracket placement and indirect-bonding model outputBSB
Clear Aligner Studio
3Shape’s indirect bonding application, integrated with named bracket systemsVEN
Maestro 3D Ortho Studio
automatic bracket positioning offering Step, Roth, Wick Alexander, Damon, MBT and Andrews, plus printed transfer guidesLIT
Nemocast
direct- and indirect-bonding guides are documentedVEN
OnyxCeph³
FA_Bonding 3D places brackets by a software algorithm with manual correction; Bonding Trays 3D designs open, semi-open and closed traysLIT

Not established from public documentation for Vision (SoftSmile), ArchForm.

A well-populated row, and rightly so. Bracket placement and printed transfer trays are established across this field and documented in the peer-reviewed literature for several of these systems by name. Nobody should choose a planner on this.

Sources

R25
Ruiz DC, Mureșanu S, Du X, Elgarba BM, Fontenele RC, Jacobs R. Unveiling the role of artificial intelligence applied to clear aligner therapy: a scoping review. Journal of Dentistry 2025;154:105564. Its authors obtained thirteen programs and ran each against one fixed list (Jan 2025, survey closed Mar 2024; peer-reviewed, open)
GM
GuideMia's own OrthoPlus documentation — the support library's automation map and workflow chapters, and the product's own status tips quoted from them (current, first-party)
BSB
Blue Sky Bio's own current documentation for the BlueSkyPlan ortho module (retrieved 10 Oct 2026, first-party)
VEN
Current vendor product pages and manuals, used only for positively documented capability, in that vendor's column (retrieved 10 Oct 2026, first-party)
SS
SoftSmile's own documentation for VISION (retrieved 10 Oct 2026, first-party)
ONX
The official OnyxCeph³ wiki, including its module index (retrieved 10 Oct 2026, first-party)
AF
ArchForm's own material (retrieved 10 Oct 2026, first-party)
LIT
Peer-reviewed studies describing a named program in use — indirect bonding tray design in OnyxCeph³, one-piece versus segmented trays in Maestro 3D, guided TAD insertion planned in orthodontic imaging software (2022–2025, peer-reviewed)
PAT
US patent literature on determining treatment stage from a current scan. Cited to show an idea is not novel, never to claim a product ships it (granted patents, not evidence of a shipping feature)

Automation is the wrong question to shop on

A free, open-access program automates every step the review measured, and the review could not establish whether any of it is AI-driven. The questions that separate these systems are narrower: whether the automation starts at the raw volume or at a mesh somebody exported, whether a person has to sit between the steps, and whether your correction to a plan survives the next recompute.